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Tag: antihistamine tolerance

Long-Term Antihistamine Use: Why They Sometimes Stop Working
Nov 29, 2025 Rob Elliott

Long-Term Antihistamine Use: Why They Sometimes Stop Working

Many people think antihistamines lose effectiveness over time due to tolerance, but research shows it's usually worsening allergies or underdosing. Learn what really causes antihistamines to seem less effective and what to do about it.

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